Login name: Password:
PluriSys publications

 

Journal articles

 

2012
Tancos, Z., C. Nemes, Z. Polgar, E. Gocza, N. Daniel, T.A.E. Stout, P. Maraghechi, M.K. Pirity, P. Osteil, Y. Tapponnier, S. Markossian, M. Godet, M. Afanassieff, Z. Bosze, V. Duranthon, P. Savatier, and A. Dinnyes, Generation of rabbit pluripotent stem cell lines. Theriogenology, 2012. submitted manuscript
Muenthaisong, S., O. Ujhelly, Z. Polgar, E. Varga, Z. Ivics, M. Pirity, and A. Dinnyes. Generation of mouse induced pluripotent stem cells from different genetic backgrounds using Sleeping Beauty transposon mediated gene transfer. Experimental Cell Research, 2012. accepted manuscript
Klincumhom, N., M. Pirity, S. Berzsenyi, O. Ujhelly, S. Muenthaisong, S. Rungarunlert, T. Tharasanit, M. Techakumphu, and A. Dinnyes. Generation of neuronal progenitor cells (NPCs) and neurons from mouse Sleeping Beauty transposon-generated induced pluripotent stem (iPS) cells. Cellular Reprogramming, 2012. accepted manuscript
Hall, V.J., M. Kristensen, M.A. Rasmussen, O. Ujhelly, A. Dinnyes, and P. Hyttel. Temporal repression of endogenous pluripotency genes during reprogramming of porcine induced pluripotent stem cells. Cellular Reprogramming, 2012. 14(3): p. 204-216.
Kobolak, J., S. Mamo, R. Rungsiwiwut, E. Csonka, G. Hadlaczky, and A. Dinnyes. Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization. Cellular Reprogramming, 2012. 14(1): p. 56-67.
Kobolak, J., M. Horsch, S. Geißler, S. Mamo, J. Beckers, and A. Dinnyes. Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation. Cellular Reprogramming, 2012. 14(1): p. 68-78.
Deshmukh, R.S., K.A. Kovacs, and A. Dinnyes. Drug discovery models and toxicity testing using embryonic and induced pluripotent stem-cell-derived cardiac and neuronal cells. Stem Cells International, 2012. (Advances in Induced Pluripotent Stem Cell Technologies)
Deshmukh, R.S., Østrup, O., Østrup, E., Veljsted, M., Niemann H., Lucas-Hahn A., Petersen, B., Li, J., Callesen, H., Hyttel, P. DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer. Epigenetics 6:2, 1-11; February 2011
Hall V., Kristensen,M., Rasmussen,M.A., Ujhelly O., Dinnyes A., Hyttel1, P. Temporal Repression of Endogenous Pluripotency Genes during Reprogramming of Porcine Induced Pluripotent Stem Cells. Cellular Reprogramming
Volume 14, Number 3, 2012
Maurotti, J., Munoz. M., Degrelle, S., Gomez, E., Louet, C., Monforte, C.D., Huot De Longchamp,P., Brochard,V., Hue, I., Caamano, J.N., Jouneau, A. Efficient Derivation of Bovine Embryonic Stem Cells Needs
More Than Active Core Pluripotency Factors.
Accepted 1 May 2012. Molecular Reproduction & Development (2012)

Marks, H, Kalkan, T, Menafra, R, Denissov, S, Jones, K, Hofemeister, H, Nichols, J, Kranz, A, Stewart, AF, Smith, A, & Stunnenberg, HG (2012). The Transcriptional and Epigenetic Foundation of Ground State Pluripotency. Cell 149, 590-604.


2011
Rungarunlert, S., R. Rungsiwiwut, S. Suphankong, S. Panasophonkul, P. Kamthorn, V. Pramuan, M. Pirirty, A. Dinnyes, T. Tharasanit, M. Techakumphu. Comparative characterization of four mouse parthenogenetic embryonic stem (pES) cell lines, Thai Journal Vet. Med, 2011. 41(2): p. 143-155.
Rungarunlert, S., N. Klincumhom, I. Bock, C. Nemes, M. Techakumphu, M. Pirirty, and A. Dinnyes. Enhanced Cardiac differentiation of Mouse embryonic stem cells by use of the slow-turning, lateral vessel (STLV) bioreactor. Biotechnol Lett., 2011. 33(8): p. 1565-73.
Gao Y., Hyttel, P., Hall, V. Dynamic Changes in Epigenetic Marks and Gene Expression During Porcine Epiblast Specification. Cellular Reprogramming. Volume 13, Number 4, 2011
Gao Y., Jammes H., Rasmussen M.A., Oestrup, O.,Beaujean,N., Hall1 V., Hyttel1, P. Epigenetic regulation of gene expression in porcine epiblast, hypoblast, trophectoderm and epiblast-derived neural progenitor cells. Epigenetics 6:9, 1149-1161; September 2011
Petkov, S.G., Marks, H., Klein,T., Garcia, R.S., Gao,Y., Stunnenberg,H., Hyttel,P. In vitro culture and characterization of putative porcine embryonic germ cells derived from domestic breeds and Yucatan mini pig embryos at Days 20–24 of gestation. Stem Cell Research (2011) 6, 226–237
Rasmussen, M.A., Hall, V.J., Carter, T.F., Hyttel, P. Directed differentiation of porcine epiblast-derived neural progenitor cells into neurons and glia. Stem Cell Research (2011) 7, 124–136
Wolf, X.A., Rasmussen, MA., Schauser,K., Jensen, AT., Schmidt, M., Hyttel,P. OCT4 Expression in Outgrowth Colonies Derived from Porcine Inner Cell Masses and Epiblasts. Reprod Dom Anim 46, 385–392 (2011)
Wolf, X.A., Serup,P., Hyttel, P. Three-Dimensional Localisation of NANOG, OCT4, and E-CADHERIN in Porcine Pre- and Peri-Implantation Embryos. Develelopmental Dynamics 240:204–210, 2011
Wolf, X.A., Serup,P., Hyttel, P. Three-Dimensional Immunohistochemical Characterization of Lineage Commitment by Localization of T and FOXA2 in Porcine Peri-implantation Embryos. Dvelopmental Dynamics 240:890–897, 2011
Bernardo, AS., Faial, T., Gardner, L., Niakan, KK., Ortmann, D., Senner, CE., Callery, EM., Trotter, MW., Hemberger., Smith, JC., Bardwell, L ., Moffett, A., Pedersen. RA. BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages. Cell Stem Cell Volume: 9 Issue: 2 Pages: 144-155. 2011.

 

2010
Pirity, M., A. Dinnyes. Tbx3: another important piece fitted into the pluripotent stem cell puzzle. Stem Cell research&therapy, 2010. 1(2): p. 12.
Mamo, S., J. Kobolak, I. Borbíró, T. Bíró, I. Bock, A. Dinnyes. Gene targeting and Calcium handling efficiencies in mouse embryonic stem cell lines. World Journal stem cells, 2010. 2(6): p. 127-140.
Kobolak, J., S. Bodo, R. Rungsiwiwut, Q.G. Meng, M. Adorjan, P. Virutamasen, M. Techakumphu, A. Dinnyes. Generation of Mouse Embryonic Stem Cell Lines from Zona-Free Nuclear Transfer Embryos. Cellular Reprogramming, 2010. 12(1): p. 105-113.
Gao Y., Poul H., Vanessa J. H. Regulation of H3K27me3 and H3K4me3 During Early Porcine Embryonic Development. Molecular Reproduction & Development 77:540– 549 (2010)
Hall, V. J., Jacobsen J.J., Rasmussen, M.A., Hyttel, P. Ultrastructural and Molecular Distinctions Between the Porcine Inner Cell Mass and Epiblast Reveal Unique Pluripotent Cell States. Developmental Dynamics 239:2911–2920, 2010
Lazzari, G.; Colleoni, S.; Lagutina, I.; Crotti, G.; Turini, P., Tessaro, I.; Brunetti, D.; Duchi, R.; Galli, C. Short-term and long-term effects of embryo culture in the surrogate sheep oviduct versus in vitro culture for different domestic species. Theirogenology. 73:6. P. 748-757. 2010
Colleoni, S.; Galli, C.; Giannelli, SG.; Armentero, MT.; Blandini, F., Broccoli, V.; Lazzari, G. Long-term culture and differentiation of CNS precursors derived from anterior human neural rosettes following exposure to ventralizing factors. Experimental Cell Research. 316:7 P. 148-1158. 2010


2009
Rungarunlert, S., M. Techakumphu, M. Pirity, and A. Dinnyes. Embryoid body formation from embryonic and induced pluripotent stem cells: Benefits of bioreactors. World Journal stem cells, 2009. 1(1): p. 11-21
Carstea, A., Pirity, M., Dinnyes,A. Germline competence of mouse ES and iPS cell lines: Chimera technologies and genetic background. World Journal stem cells, 2009. 1(1): p. 22-29.

 

Abstracts in peer-reviewed journals

 

2012
Tancos, Z., O. Ujhelly, M.K. Pirity, and A. Dinnyes. Isolation of rabbit pluripotency genes to generate rabbit induced pluripotent stem cells. Reproduction Fertility and Development, 2012. 24(1): p. 223-224.
Rasmussen, M.A., V.J. Hall, S.G. Petkov, O. Ujhelly, M.K. Pirity, A. Dinnyes, H. Niemann, P. Hyttel. Reprogramming of porcine neural progenitor cells to induced pluripotent stem cell-like cells. Reproduction Fertility and Development, 2012. 24(1): p. 217-218.
Rasmussen, M.A., V.J. Hall, S.G. Petkov, O. Ujhelly, M. Pirity, A. Dinnyes, H. Niemann, P. Hyttel, Reprogramming of porcine epiblast-derived neural progenitor cells to pluripotency. Reproduction Fertility and Development, 2012. 24(1): p. 289.
Dinnyes, A., M.K. Pirity, E. Gocza, P. Osteil, N. Daniel, Z. Tancos, Z. Polgar, P. Maraghechi, O. Ujhelly, C. Nemes, T. Stout, Y. Tapponnier, Z. Bosze, A. Jouneau, M. Afanassieff, P. Savatier. Generation of rabbit pluripotent stem cell lines. Reproduction Fertility and Development, 2012. 24(1): p. 286.

 

2011
Varga, E., C. Nemes, N. Klincumhom, Z. Polgar, S. Muenthaisong, O. Ujhelly, M. Pirity, A. Dinnyes. Generation of mouse induced pluripotent stem cells from different genetic backgrounds by excisable lentiviral system. ISSCR International Society for Stem Cell Research 9th Annual Meeting Friday Poster Abstracts, 2011: p. 180.
Rungarunlert, S., N. Klincumhom, C. Nemes, M. Techakumphu, M.K. Pirity, A. Dinnyes. Mass Production Of Nkx2.5-Positive Cardiac Progenitor Cells Derived From Mouse Embryonic Stem Cells In Slow-Turning Lateral Vessel For Cell Transplantation And Drug Testing. Reproduction Fertility and Development, 2011. 23(1): p. 244.
Nemes, C., E. Varga, Z. Polgar, N. Klincumhom, M. Pirity, A. Dinnyes. Generation of mouse induced pluripotent stem cells by protein transduction. ISSCR International Society for Stem Cell Research 9th Annual Meeting Friday Poster Abstracts, 2011: p. 181.
Muenthaisong, S., O. Ujhelly, E. Varga, A.C. Carstea, Z. Ivics, K.M. Pirity, A. Dinnyes. Generation Of Mouse Induced Pluripotent Stem Cells From Various Genetic Background By Sleeping Beauty Transposon-Mediated Gene Transfer. Reproduction Fertility and Development, 2011. 23(1): p. 243-244.
Dinnyes, A., O. Ujhelly, C. Nemes, S. Muenthaisong, S. Rungarunlert, N. Klincumhom, E. Varga, A. Lauko, R. Tosoki, M. Jakus, Z. Polgar, A. Feher, M. Pirity, K.A. Kovacs. Pluripotent stem cell-derived cardiac and neural cells for toxicity testing and regenerative medicine. Abstracts of the IV Congress of Polish Biotechnology and “IV EUROBIOTECH 2011” Central European Congress of Life Sciences, 2011: p. 79.


2010
Muenthaisong, S., O. Ujhelly, E. Varga, Z. Ivics, M. Pirity, A. Dinnyes. Generation of induced pluripotent stem cells from mouse embryonic fibroblasts by sleeping beauty transposon. Transgenic Research, 2010. 19(2): p. 344.


2009
Rungarunlert, S., K. Tar, S. Muenthaisong, M. Techakumphu, M. Pirity, A. Dinnyes. Differentiation Of Mouse Embryonic Stem Cells Into Cardiomyocites By Using Slow Turning Lateral Vessel (STLV/Bioreactor). Reproduction Fertility and Development, 2010. 22(1): p. 355.


Conference posters


2012
Táncos, Z., O. Ujhelly, M. Pirity, and A. Dinnyés. Isolation of rabbit pluripotency genes to generate rabbit induced pluripotent stem cells. Annual Conference of the International Embryo Transfer Society (IETS). 7-10. January 2012. Phoenix, Arizona, USA
Rasmussen, M., V.J. Hall, S. Petkov, O. Ujhelly, M.K. Pirity, A. Dinnyes, H. Niemann, P. Hyttel. Reprogramming of porcine neural progenitor cells to induced pluripotenet stem cell-like cells. 38th Annual Conference of the IETS. January 7-10 2012. Phoenix, Arizona
Pajer, K., C. Nemes, K.A. Kovacs, M. Pirity, A. Dinnyes, A. Nogradi. Induced pluripotent stem cells rescue injured motoneurons following ventral root avulsion. in IBRO International Workshop 2012.19-21 January. 2012. Szeged, Hungary
Muenthaisong, S., M.A. Rasmussen, V.J. Hall, O. Ujhelly, A. Dinnyes, P. Hyttel. In vitro differentiation potential of porcine induced pluripotent stem cell-like cells derived from neural progenitor cells. in ISSCR 10th Annual Meeting. 13-16. June 2012. Yokohama, Japan
Kudo, M., M.A. Rasmussen, V.J. Hall, R.S. Deshmukh, K.A. Kovacs, A. Dinnyes, P. Hyttel. Recapitulating neural development in vitro in the pig - ultrastructural aspects. Symposium on Functional Genomics of Early Development in Livestock. 24-26 July 2012. Banff, Canada
Fröhlich, T., M. Kösters, A. Dinnyes, A. Jouneau, G.J. Arnold. Multiplexed proteome analysis of nuclear transfer-derived stem cells and their fertilization-derived counterparts. From Genome to Proteome: open innovations. 26-30. August 2012. Siena, Italy

Khan D., Dubé D., Gall L., Peynot N., Ruffini S., Laffont L., Degrelle S., Jouneau A., Duranthon V. Expression of pluripotency master regulators during early development of bovine embryos. Abstract. EMBO meeting 2012. 2-25 September, Niece, France

 

 

2011
Varga, E., C. Nemes, N. Klincumhom, Z. Polgar, S. Muenthaisong, O. Ujhelly, M. Pirity, A. Dinnyes. Generation of mouse induced pluripotent stem cells from different genetic backgrounds by excisable lentiviral system.ISSCR meeting. 15-18. June 2011. Toronto, Canada
Rungarunlert, S., N. Klincumhom, C. Nemes, M. Techakumphu, M. Pirity, A. Dinnyes. Mass production of Nkx2.5-positive cardiac progenitor cells derived from mouse embryonic stem cells in slow-turning lateral vessel for cell transplantation and drug testing. IETS 37th Annual Conference. 8-12. January 2011. Orlando, USA
Nemes, C., E. Varga, Z. Polgar, N. Klincumhom, M. Pirity, A. Dinnyes. Generation of mouse induced pluripotent stem cells by protein transduction. in ISSCR 9th Annual Meeting. June 15-18, 2011 2011. Toronto, Ontario, Canada
Muenthaisong, S., O. Ujhelly, E. Varga, A.C. Carstea, Z. Ivics, M. Pirity, and A. Dinnyes. Generation of mouse induced pluripotent stem cells from various genetic background by sleeping beauty transposon mediated gene transfer. in IETS 37th Annual Conference. 8-12. January 2011. Orlando, USA
Veillard,Anne-Clemence, Marks ,Hendrik, Jouneau,Luc, Maruotti,Julien, Jammes, Hélène, Stunnenberg, Henk, Jouneau, Alice. Epigenetic Characterization of Epiblast Stem Cells Derived from Fertilized And Nuclear-Transferred Mouse Embryos. In 1st annual Cambridge Stem Cell international symposium: Pluripotency and Development. 06 July 2011- 07 July 2011.


2010

Muenthaisong, S., O. Ujhelly, E. Varga, Z. Ivics, M. Pirity, and A. Dinnyés. Generation of induced pluripotent stem cells from mouse embryonic fibroblasts by Sleeping Beauty Transposon. in 9th Transgenic Technology Meeting (TT2010). 22-24 March 2010. Berlin, Germany

 

2009
Lazzari, G., Colleoni, S., Galli, C.The use of 3i medium for the derivation of bovine emryionic stemm cells. ISSCR meeting. 10-12, July. 2009. Barcelona.

2008
Rungalunlert, S., S. Muenthaisong, A. Feher, I. Bock, K. Tar, M. Techakumphu, M. Pirity, A. Dinnyes. Differentiation of embryonic stem (ES) cells into cardiac lineage. MBK Napok. 2008: Godollo, Hungary
Rasmussen, M,A., Hall, V.J., Hyttel, P. Derivation of neural progenitor cells from porcine epiblast cells. 2010. IETS conference. Januar 9-12. 2010. Cordoba


Conference presentations
2012
Dinnyes, A., C. Nemes, S. Muenthaisong, N. Klincumhom, S. Rungarunlert, E. Varga, Z. Tancos, A. Lauko, R. Tosoki, M. Jakus, Z. Polgar, S. Berzsenyi, H. Raveh-Amit, K.A. Kovacs, A. Feher. Pluripotent stem cell-derived differentiated cells for toxicity testing and regenerative medicine. Resolve International Meeting "Tissue Remodeling in Ageing and Disease - Emerging Insights into a Complex Pathology". 28. March 2012. Vienna, Austria
Dinnyes, A., S. Berzsenyi, A.K. Kovacs, Y. Martinez, D. Ye, H. Raveh-Amit, and C. Nemes. Induced pluripotent stem cells to create cardiac, neuronal and smooth muscle tissue models. Advances in In-Vitro Cell and Tissue Culture and 4th Annual Quasi-Vivo User Group Meeting. 22-23 May 2012. Utrecht, The Netherlands
Dinnyes, A., 3D Neural Tissue from Stem Cells. Advances in In-Vitro Cell and Tissue Culture and 4th Annual Quasi-Vivo User Group Meeting, Utrecht, The Netherlands. 22. May 2012
Dinnyes, A. Induced pluripotent stem cells to create 3D neuronal tissue models. 75th Anniversary of Albert Szent-Györgyi's Nobel Prize Award. 25. March 2012. Szeged, Hungary


2011
Táncos, Z., M. Pirity, and A. Dinnyés. Progress and bottlenecks towards generating germline chimera forming induced pluripotent stem cells in rabbit, „Novel findings in rabbit ES and iPS cell establishment”. 4th International Rabbit Biotechnology Meeting. 1. July 2011. Budapest, Hungary
Polgar, Z., A. Dinnyes. Nuclear transfer technology in rabbits. 4th International Rabbit Biotechnology Meeting. 1 July 2011. Budapest, Hungary
Muenthaisong, S., O. Ujhelly, E. Varga, Z. Polgar, A.C. Carstea, Z. Ivics, M. Pirity, A. Dinnyes. Induction of pluripotent stem (ips) cells by Sleeping Beauty Transposon mediated gene transfer. 3rd conference on "A Focus On Stem Cells". 10-11 March 2011. Debrecen, Hungary
Dinnyes, A., O. Ujhelly, C. Nemes, S. Muenthaisong, S. Rungarunlert, N. Klincumhom, E. Varga, A. Lauko, R. Tosoki, M. Jakus, Z. Polgar, A. Feher, M. Pirity, K.A. Kovacs. Pluripotent stem cell-derived cardiac and neural cells for toxicity testing and regenerative medicine. in IV. Congress of Polish Biotechnology. 12-15 October 2011. Krakow, Poland


2010
Pirity, M., A. Dinnyés. Transzgenetikus és knock out állatok, őssejtvonalak az ADME kutatásban. in Farmakokinetika és gyógyszermetabolizmus szimpózium. 14-16. April 2010. Galyatető, Hungary
Dinnyes, A., O. Ujhelly, C. Nemes, S. Muenthaisong, S. Rungarunlert, N. Klincumhom, E. Varga, Z. Polgar, M. Pirity. Pluripotent stem cells for drug testing and regenerative medicine. in Proceedings of the Advances in Medical Biotechnology Conference. 29 Nov. - 1 Dec. 2010. Pécs, Hungary
Dinnyes, A., M. Pirity, O. Ujhelly, C. Nemes. Testi sejtek genetikai újraprogramozása klónozással és indukált pluripotens őssejt módszerekkel transzgenikus modell állatok és sejtes tesztrendszerek létrehozására. TOX 2010. 13-15. Oct. 2010. Galyatető, Hungary

 


2009
Pirity, M., O. Ujhelly, C. Nemes, S. Muenthaisong, S. Rungarunlert, N. Klincumhom, E. Varga, Z. Polgar, A.C. Carstea, S. Bodo, A. Dinnyes. Testi sejtek genetikai újraprogramozásának lehetőségei – Tools for Genetic Reprogramming of Somatic Cells. MBK Napok. 30. Nov - 1. Dec. 2009. Gödöllő, Hungary


2008
Dinnyes, A. Systems biology to understand cell pluripotency in mammalian models (Platform session). The 5th Annual Conference of the Asian Reproductive Biotechnology Society. 26-30 November 2008. Kunming, Yunnan, China
Dinnyes, A. Plurisys: A new european project to understand cell pluripotency in multiple mammalian models. BIT Life Sciences 1st Annual World Congress of Regenerative Medicine & Stem Cell. 2-4. December 2008. Foshan, China

 

Media coverage
2009
Dinnyes, A., ”LÁNGÉSZ” project roundtable. Hungarian Academy of Sciences. 10 November. 2009. Budapest, Hungary
EU FP7 “Research Connections” Conference 7-8. May 2009. Prague Exhibition: Stand nr 31 MyScience – poster on display